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An important next step: New scientific research & interview series announced today

2023.04.01 09:04 Accomplished_Oil527 An important next step: New scientific research & interview series announced today

We are pleased to inform you of more significant progress towards scientific understanding and awareness of Post-Finasteride Syndrome.
Upcoming scientific research: Opening a new line of scientific investigation
As you may have already heard, our first scientific study at The University of Kiel is already underway. The objective of these efforts is to uncover more pathomechanistic clues about the disease - a necessary step to gain a better understanding of why the findings of significant and widespread gene deregulation demonstrated by Baylor might be occurring.
To gain a complete understanding of this disease, however, we are now going to be looking into possible predisposition(s) to PFS. Today, we are announcing new research to support this objective, provisionally titled Investigating genetic factors involved in the development and onset of Post-Finasteride Syndrome.
Tampere University in Finland will begin investigating possible genetic factors involved in developing Post-Finasteride Syndrome. This research will continue building upon the important results from Baylor College of Medicine. These landmark findings demonstrated significant deregulation of gene expression in PFS patient tissue which correlated to observed biological differences in patients and their self-reported symptoms. While Baylor’s results indicate a what, we need to continue expanding into the why with more modern investigative techniques.
These efforts, combined with those already underway at The Institute for Human Genetics in Germany, hope to provide a more complete understanding of PFS, and why some patients experience persistent and severe health problems after discontinuing finasteride.
In this study, researchers will use a technique known as Whole Genome Sequencing (WGS) to analyse a cohort of PFS patients, looking for potential genetic factors that may predispose patients to developing the disease. This type of study has been clearly recommended as an appropriate next step by multiple publications, including Baylor College of Medicine. The aims of investigating possible genetic factors involved in PFS are:
Understanding possible genetic factors involved in Post-Finasteride Syndrome could provide another path to accurate disease modelling in animals. Insights uncovered through research into patient genetics, along with potential insights from our existing line of scientific investigation, can contribute to establishing a disease model, with the objective of understanding the core pathomechanism and hopefully, an eventual target for precision medicine treatment of PFS. An understanding of the predisposition will also:
Specifically, this study will use WGS to analyse the entire genome of 150 PFS patients compared to a group of healthy controls. WGS in principle allows the detection of disease relevant genomic variants beyond the exome such as DNA structural alterations, deep intronic variants, variants in non-coding regions, or repeat expansions and may improve variant calling in homologous sequences. It represents a novel, distinct diagnostic tool that targets genes and goes beyond the coding region and allows elucidation of established and novel non-coding genomic diseases.
The researchers involved in this project are accomplished in their fields and have a genuine interest in the disease. After extensive consultation and collaboration on our previous project, they are also aware of the multisystemic nature of PFS and other key peculiarities involved. The supervising lead, Professor Alfonso Urbanucci, has previously published in Cell reports evidence that overexpression of the AR is able to drive genome-wide chromatin relaxation and gene expression alteration in refractory prostate cancer. Collaborative input will be provided by Professor Johanna Schleutker, an accomplished geneticist.
We again appreciate any support that patients, loved ones and supporters can provide. We understand the scarcity of resources available in our community and do not take any decision about the allocation of those resources lightly. This is a path that has been recommended by almost every researcher we’ve consulted with, including preeminent researchers operating some of the largest facilities in the world.
Generously, researchers involved have again offered their support at a heavily discounted rate. We will not be required to pay salary cost for the researchers involved, which makes what would usually be quite-costly far more palatable.
As such, we are setting a fundraising target of €200,000. This has again been supplemented by the generous donations that supporters have continued to make even after the Kiel study was funded. While €200,000 is the “breakeven” figure for the study, we must again remind patients that research is largely a chicken-and-egg scenario. The more funds available, the easier it is to begin new research when insights become available.
You can donate here: pfsnetwork.org/donate
PFS Network now a registered 501(c)(3) organisation
After many months of waiting, we are pleased to announce we have received 501c3 status in the United States. This means that all donations made from US tax residents are now tax-deductible. We believe this also means patients can retroactively make tax-deductible claims for donations over the previous years, but please check with a tax expert.
Patient recruitment
We will be prioritising patients who completed the patient survey on Propeciahelp for this study, in order of those most severely affected. If you participated in the survey, you will be receiving an email in the coming days with an invitation to participate. If you receive this email, please follow the link to the form provided. Once we have exhausted this list, we will also be asking newer patients to come forward. When you apply, you will be asked to provide a link to your propeciahelp member story or Reddit profile so we can verify your post history and when you entered the community.
Please do not email or reach out until we have asked for more volunteers. We do not have the manpower to manually sort through applications.
As this study will be conducted remotely, it is vital we validate each participant is in fact a patient. It will also add weight to the study scientifically. For this reason, we are prioritising patients who completed our patient survey. This does not mean that you will not have a chance to participate if you didn’t complete the survey - it is highly likely we will not have 150 responses from survey participants. This study requires 150 patient samples to go ahead. Control data will be provided by a data bank containing healthy controls that is frequently used for genetics studies. The material required will be a blood sample.
Collection can be done remotely, and will be managed by our partner Dante Labs, a highly-respected third-party company that provides sequencing services for large laboratories, hospitals and institutions. If you are interested, Dante will send you a blood collection kit via mail, which you will send back to their lab once complete. You do not need to leave your house to collect the sample and the kit is very straightforward to use. It will not cost you anything to participate.
Faces of the disease: New awareness campaign
After two decades, it finally feels like this disease is emerging from the shadows. While public accounts were sporadic in decades prior, in recent years we’ve seen a surge in patients speaking openly about the devastating effects of PFS. It is immensely encouraging that this is happening beyond our own efforts.
After much delay, we have begun releasing the second season of our patient interview series on our YouTube channel: https://www.youtube.com/channel/UCQXyXbJNqxzjEhPp5RVI88A
We will be releasing one episode a month and we encourage you to share them widely, like and comment. These simple actions will help these accounts rank higher in search results on what is an important platform for awareness. Again, we are indebted to our five guests for their bravery.
Our group has consistently maintained that research is only one - albeit very important - path towards understanding and acceptance of this disease. Anonymous usernames on a forum can be easily dismissed, but real humans cannot. We encourage anyone interested in speaking out to come forward as we begin recording more episodes shortly.
This opportunity represents another significant step in bringing this disease out of the shadows. We hope you are able to support where possible.
Thank you again for your continued courage, PFS Network team
submitted by Accomplished_Oil527 to FinasterideSyndrome [link] [comments]


2023.04.01 08:40 Fancy-Designer5716 Binge read the entire manga in about 3 days.

submitted by Fancy-Designer5716 to JuJutsuKaisen [link] [comments]


2023.04.01 08:19 NateBoyer2000 Did they finally fix the bug on mobile that switched to desktop when switching languages?

Every time I switched from english Wikipedia to French on mobile it would take me to “fr.wikipedia.org” so I would have to manually type “fr.m.wikipedia.org”, but recently I haven’t had to do this, was this a recent bug fix?
submitted by NateBoyer2000 to wikipedia [link] [comments]


2023.04.01 07:38 PianistMajor6524 [WTS] HOLOSUN HE407C GR X2 [A+]

Howdy!
() Here to sell my Holosun HE407C GR X2 pistol sight. It’s rated an A+ condition. ()
Comes With battery, 4 sets of Screws, Sight Tool, lens cloth and the User Manual. I’m asking $200 first class shipping.
You can read up on this sight from holosun here
If anything is off please let me know.
I prefer PPFF Or Venmo. Dibs then chat/message rules apply.
submitted by PianistMajor6524 to GunAccessoriesForSale [link] [comments]


2023.04.01 07:16 Descrypt1 Understanding IRS Form 8949 for Crypto Investors: A Complete Guide

Cryptocurrency investment is increasingly being seen as an unmissable asset class and gaining legitimacy. With this increased popularity comes the need to report gains and losses for tax purposes. One crucial aspect of reporting these gains and losses is the IRS Form 8949. This form is specifically designed for investors who must report capital gains or losses from selling or exchanging property, a group that now includes cryptocurrency. If you're a crypto investor, this post will walk you through completing Form 8949.

Requirements for Filing Form 8949

To file Form 8949 for cryptocurrency transactions, investors must report any sales, exchanges, or dispositions of cryptocurrency, including instances where cryptocurrency is used to purchase goods or services. Transactions of less than $200 are exempt, and no reporting is required. However, transactions exceeding this amount must be reported.
Please note that the information provided is for educational purposes only. You should always consult a qualified tax professional for accurate and up-to-date guidance on how to fill out Form 8949. This will ensure misunderstandings and errors will not arise, especially from laws specific for your area of residence.

How to Fill Out Form 8949

Once you've determined that you must report your crypto transactions on Form 8949, the next step is filling out the form accurately and completely. Here's a step-by-step guide to help you navigate the process:

  1. Start by downloading a blank copy of 8949 tax form from the IRS website.
  2. Enter your personal information, including your name, social security number, or taxpayer identification number, and the tax year you are filing for.
  3. Identify the asset being sold or exchanged by filling columns (a) and (b). In column (a), you'll list the name of the asset, such as "Bitcoin" or "Ethereum." In column (b), you'll list the date you acquired the asset.
  4. In column (c), list the date you sold or exchanged the asset.
  5. In column (d), enter the proceeds from the sale or exchange. This includes any cash or cryptocurrency you received due to the transaction.
  6. In column (e), enter the cost basis of the asset. This is the asset's original purchase price plus any additional costs associated with acquiring or holding the asset, such as fees or commissions. If you acquired the asset through mining or staking, your cost basis is the asset's fair market value on the date you received it.
  7. In column (f), calculate the gain or loss from the transaction by subtracting the cost basis from the proceeds. If the result is a positive number, you have a capital gain. If the results are in negative figures, you have a capital loss.
  8. Repeat this process for each transaction you need to report on Form 8949, and make sure the total gains and losses are accurately calculated and reported on your tax return.
It's important to take your time and fill out 8949 tax form carefully to avoid errors or discrepancies that could trigger an internal revenue service audit or result in an incorrect tax bill.

Common Mistakes to Avoid

While filling out Form 8949, it's crucial to avoid common mistakes that can lead to internal revenue service penalties. Common mistakes include incorrect reporting, missing information, and failure to attach Form 8949 to your tax return. It's also important to double-check all entries to ensure accuracy.

How to Descrypt Crypto Transactions on IRS Form 8949

The IRS requires taxpayers to report all cryptocurrency transactions. However, tallying these transactions can take time and effort, and the manual data entry processes are prone to error. Descrypt is an essential platform that can help investors improve their reporting accuracy.
By automatically tracking all crypto transactions, traders can rest easy knowing they have accurately provided the relevant information to file their taxes accurately. Connect your wallet or exchange accounts directly to Descrypt, and the platform will generate a comprehensive report that includes all the necessary details for filing Form 8949.

Wrapping Up

Filing taxes for crypto investments can be complex, but understanding how to complete Form 8949 is crucial. This blog post provides a comprehensive guide to understanding and completing Form 8949 for crypto investors. This is a complex form with little room for error, and traders need to become familiar with this process.
Descrypt can significantly reduce the stress of tax season through automation. By giving accurate reports to investors, managing capital gains tax liabilities has never been easier nor safer. Click here and connect your wallet or exchange to Descrypt to generate your most accurate crypto portfolio and transaction report.
submitted by Descrypt1 to u/Descrypt1 [link] [comments]


2023.04.01 05:13 ROKCVIEW My Very First 200

My Very First 200
It all came down to one pin in the end, felt great and it was on cosmic night🤯
submitted by ROKCVIEW to Bowling [link] [comments]


2023.04.01 04:47 Rxmenqt Just got a new cat tree and thought I’d share it here :D

Just got a new cat tree and thought I’d share it here :D submitted by Rxmenqt to cats [link] [comments]


2023.04.01 03:53 Old-Initiative1867 Tested a new strategy

I’ve had this running for about 20 minutes
submitted by Old-Initiative1867 to Stake [link] [comments]


2023.04.01 03:13 10011110 When your gear does nothing. :D

When your gear does nothing. :D submitted by 10011110 to playrust [link] [comments]


2023.04.01 03:00 gcp_updates_bot March 31, 2023 GCP release notes

Link

GCP release notes for March 31, 2023

Release notes

Access Approval ==> Changed
Access Approval supports Cloud Composer in the GA stage.
Anthos clusters on VMware ==> Feature
Anthos clusters on VMware 1.12.7-gke.19 is now available. To upgrade, see Upgrading Anthos clusters on VMware . Anthos clusters on VMware 1.12.7-gke.19 runs on Kubernetes 1.23.17-gke.900.
The supported versions offering the latest patches and updates for security vulnerabilities, exposures, and issues impacting Anthos clusters on VMware are 1.14, 1.13, and 1.12.
==> Feature * Added admin cluster CA certificate validation to the admin cluster upgrade preflight check. * Allow storage DRS to be enabled in manual mode.
==> Fixed * Fixed an issue where using gkectl update to enable Cloud Audit Logs did not work. * We now backfill the OnPremAdminCluster OSImageType field to prevent an unexpected diff during update. * Fixed an issue where a preflight check for Seesaw load balancer creation failed if the Seesaw group file already existed. Anthos clusters on bare metal ==> Feature
Cluster lifecycle improvements 1.13.1 and later
Starting with Anthos clusters on bare metal release 1.13.1, you can use the Google Cloud console or the gcloud CLI to create admin clusters. For more information, see the documentation for your version of Anthos clusters on bare metal:
Cloud Bigtable ==> Feature
Cloud Bigtable instance and table metadata is now automatically synced to Data Catalog, a feature of Dataplex, for improved data discovery and governance. Metadata is not synced for a project with an organization policy that restricts resource locations. To get started, see Manage data assets using Data Catalog . This feature is available in Preview .
==> Changed
You can now use Key Visualizer for Cloud Bigtable to analyze tables that are at least 1 GB. Previously, the minimum table size required for Key Visualizer was 30 GB. For more information on troubleshooting with Key Visualizer, see the Key Visualizer overview .
Cloud Logging ==> Changed
Effective 1 April 2023, storage costs apply to logs data retained longer than 30 days. For pricing details, see Cloud Logging pricing summary . Prior to 1 April 2023, there are no charges for retaining logs longer than 30 days. To review the billable storage for your log buckets, go to the Logs Storage page of the Google Cloud console.
Cloud Spanner ==> Feature
Cloud Spanner integration with Data Catalog is now available in Preview. Data Catalog is a fully managed, scalable metadata management service within Dataplex. It automatically catalogs metadata about Cloud Spanner instances, databases, tables, columns, and views. For Preview, integration with Data Catalog is not available in the europe-central2 region.
For more information, see Manage resources using Data Catalog .
Cloud TPU ==> Changed
Cloud TPU now supports Tensorflow 2.11.1. For more information see the TensorFlow 2.11.1 release notes .
Cloud Workstations ==> Feature
You can use a pre-customized snapshot as the source of a Persistent Disk in Cloud Workstations. For more information, see About disk snapshots . See also the sourceSnapshot within GceRegionalPersistentDisk field added to the following REST API resources: workstation configurations , and source_snapshot in the following RPC resources: workstations.v1beta .
==> Feature
Cloud Workstations is available in the following region:
  • asia-northeast1 (Japan)
    For more information, see Locations .
Compute Engine ==> Feature
Generally available: You can use the Regional disk replica state metric in Cloud Monitoring to track the states of your regional Persistent Disk zonal replicas. You can also use the metric data to determine the replication state of your regional Persistent Disk volumes.
Learn more about zonal replication for regional Persistent Disk and how to monitor the states of regional Persistent Disk zonal replicas .
Google Cloud VMware Engine ==> Changed
VMware Engine nodes are now available in the following additional region:
  • Santiago ( southamerica-west1 ) Google Kubernetes Engine ==> Changed
    (2023-R08) Version updates
    GKE cluster versions have been updated.
New versions available for upgrades and new clusters
The following Kubernetes versions are now available for new clusters and for opt-in control plane upgrades and node upgrades for existing clusters. For more information on versioning and upgrades, see GKE versioning and support and Upgrades .
==> No channel
Note:
Your clusters might not have these versions available. Rollouts begin on the day of the note and take four or more business days to be completed across all Google Cloud zones.
  • The following control plane versions are now available:
  • The following node versions are now available:
  • Version 1.24.10-gke.2300 is now the default version.
  • The following control plane versions are no longer available:
    • 1.21.14-gke.14600
    • 1.22.17-gke.4000
    • 1.22.17-gke.4300
    • 1.23.14-gke.1800
    • 1.23.15-gke.1400
    • 1.23.15-gke.1900
    • 1.23.16-gke.200
    • 1.23.16-gke.1100
    • 1.24.9-gke.2000
    • 1.25.6-gke.1000
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.20 to 1.21.14-gke.15800 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.21 to 1.22.17-gke.5400 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.22 to 1.23.16-gke.1400 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.23 to 1.23.16-gke.1400 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.24 to 1.24.10-gke.2300 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.25 to 1.25.7-gke.1000 with this release.
    ==> Stable channel
Note:
Your clusters might not have these versions available. Rollouts begin on the day of the note and take four or more business days to be completed across all Google Cloud zones.
  • The following versions are now available in the Stable channel:
  • Version 1.24.10-gke.2300 is now the default version in the Stable channel.
  • The following versions are no longer available in the Stable channel:
    • 1.21.14-gke.14600
    • 1.22.17-gke.4000
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.20 to 1.21.14-gke.15800 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.21 to 1.22.17-gke.5400 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.22 to 1.23.16-gke.1400 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.24 to 1.24.10-gke.2300 with this release.
    ==> Regular channel
Note:
Your clusters might not have these versions available. Rollouts begin on the day of the note and take four or more business days to be completed across all Google Cloud zones.
  • The following versions are now available in the Regular channel:
  • Version 1.24.10-gke.2300 is now the default version in the Regular channel.
  • The following versions are no longer available in the Regular channel:
    • 1.21.14-gke.18100
    • 1.22.17-gke.5400
    • 1.24.9-gke.3200
    • 1.25.6-gke.1000
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.20 to 1.21.14-gke.18800 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.21 to 1.22.17-gke.6100 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.22 to 1.23.16-gke.2500 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.23 to 1.24.10-gke.2300 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.24 to 1.24.10-gke.2300 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.25 to 1.25.7-gke.1000 with this release.
    ==> Rapid channel
Note:
Your clusters might not have these versions available. Rollouts begin on the day of the note and take four or more business days to be completed across all Google Cloud zones.
  • The following versions are now available in the Rapid channel:
  • Version 1.26.2-gke.1000 is now the default version in the Rapid channel.
  • The following versions are no longer available in the Rapid channel:
    • 1.22.17-gke.5400
    • 1.23.16-gke.1400
    • 1.24.11-gke.1000
    • 1.25.6-gke.1000
    • 1.26.1-gke.1500
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.21 to 1.22.17-gke.6100 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.22 to 1.23.16-gke.2500 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.23 to 1.24.12-gke.500 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.24 to 1.25.7-gke.1000 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.25 to 1.25.7-gke.1000 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.26 to 1.26.2-gke.1000 with this release.
    ==> Changed
    (2023-R08) Version updates
  • The following versions are now available in the Stable channel:
  • Version 1.24.10-gke.2300 is now the default version in the Stable channel.
  • The following versions are no longer available in the Stable channel:
    • 1.21.14-gke.14600
    • 1.22.17-gke.4000
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.20 to 1.21.14-gke.15800 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.21 to 1.22.17-gke.5400 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.22 to 1.23.16-gke.1400 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Stable channel will be upgraded from version 1.24 to 1.24.10-gke.2300 with this release.
    ==> Changed
    (2023-R08) Version updates
  • The following versions are now available in the Regular channel:
  • Version 1.24.10-gke.2300 is now the default version in the Regular channel.
  • The following versions are no longer available in the Regular channel:
    • 1.21.14-gke.18100
    • 1.22.17-gke.5400
    • 1.24.9-gke.3200
    • 1.25.6-gke.1000
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.20 to 1.21.14-gke.18800 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.21 to 1.22.17-gke.6100 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.22 to 1.23.16-gke.2500 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.23 to 1.24.10-gke.2300 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.24 to 1.24.10-gke.2300 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Regular channel will be upgraded from version 1.25 to 1.25.7-gke.1000 with this release.
    ==> Changed
    (2023-R08) Version updates
  • The following versions are now available in the Rapid channel:
  • Version 1.26.2-gke.1000 is now the default version in the Rapid channel.
  • The following versions are no longer available in the Rapid channel:
    • 1.22.17-gke.5400
    • 1.23.16-gke.1400
    • 1.24.11-gke.1000
    • 1.25.6-gke.1000
    • 1.26.1-gke.1500
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.21 to 1.22.17-gke.6100 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.22 to 1.23.16-gke.2500 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.23 to 1.24.12-gke.500 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.24 to 1.25.7-gke.1000 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.25 to 1.25.7-gke.1000 with this release.
  • Control planes and nodes with auto-upgrade enabled in the Rapid channel will be upgraded from version 1.26 to 1.26.2-gke.1000 with this release.
    ==> Changed
    (2023-R08) Version updates
  • The following control plane versions are now available:
  • The following node versions are now available:
  • Version 1.24.10-gke.2300 is now the default version.
  • The following control plane versions are no longer available:
    • 1.21.14-gke.14600
    • 1.22.17-gke.4000
    • 1.22.17-gke.4300
    • 1.23.14-gke.1800
    • 1.23.15-gke.1400
    • 1.23.15-gke.1900
    • 1.23.16-gke.200
    • 1.23.16-gke.1100
    • 1.24.9-gke.2000
    • 1.25.6-gke.1000
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.20 to 1.21.14-gke.15800 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.21 to 1.22.17-gke.5400 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.22 to 1.23.16-gke.1400 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.23 to 1.23.16-gke.1400 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.24 to 1.24.10-gke.2300 with this release.
  • Control planes and nodes with auto-upgrade enabled will be upgraded from version 1.25 to 1.25.7-gke.1000 with this release. Security Command Center ==> Feature
    Security Command Center supports CIS Google Cloud Computing Foundations Benchmark v1.3.0.
    The following detectors are new for v1.3.0:
  • Access transparency disabled
  • Cloud Asset API disabled
  • Dataproc CMEK disabled
  • Essential contacts not configured
  • Flow logs settings not recommended
    The following detectors have been updated:
  • Audit logging disabled
    For more information about Security Command Center support for standards and compliance, see the following:
  • Detectors and compliance
  • CIS Google Cloud Computing Platform Benchmarks
submitted by gcp_updates_bot to googlecloudupdates [link] [comments]


2023.04.01 01:32 Entire-Chemist-1812 Roblox just added this to mobile!

Roblox just added this to mobile!
I think its useful, what's your opinion about it?
submitted by Entire-Chemist-1812 to roblox [link] [comments]


2023.04.01 01:16 ameyano_acid Help with picking a first 4x4 guys! Freshly out of my time chippy needing some help.

Hi legends
I am a freshly qualified chippy desperate for a ute as my old faithful doesn't cut it anymore. I need it mainly for work and maybe once in a while 4wding. Budget is about 15-18k.
I have options -
2006 Hilux 200,000km automatic $20k Pretty much standard stock. Bit of a lift. Looks decent overall. Petrol V6 N70 Hilux. Rego and rwc. Clear title
2011 Mitsubishi Triton 81,500km Automatic $13k Pretty much standard stock. Looks a bit dodgy but the guy insists it's a clear title (I'll check the VIN if I go with this for clear ppsr). No rego rwc yes clear title.
2010 Nissan Navara 165,000km $15.7k D22 Manual Heavily modded with sus lifts, muddies, bunch of bells and whistles which I don't really care about but it looks like a decent car overall. Rego yes rwc yes clear title.
I have to sort it out by this weekend.
Needs - pretty much haul my tools in the canopy I'll put on it and maybe a trailer but that's a few years away atleast.
If someone more experienced could help me out with picking the right car, please do. I could stretch my budget a bit but I'll have to ask the missus for a little which she is happy to help out with but I would rather not.
I will roughly get 13-14k for my old hatchback car so that'll offset everything for me.
EDIT - The Triton was rust central. Looked like it was flooded big time so I just said no and came home.
Help a fella out. Thanks kings
submitted by ameyano_acid to 4x4Australia [link] [comments]


2023.04.01 01:12 Akenaton4815_ Hace unos meses fui a un tianguis a pensar, entre los puestos había una mesita con juguetes, aparatos eléctricos y demás cosas, de entre todo eso había ahí un Super Mario Sunshine, lo agarre y la caja del juego estaba intacta, el disco sin ningún rayón, pregunté cuánto era y OMG 50$!

Hace unos meses fui a un tianguis a pensar, entre los puestos había una mesita con juguetes, aparatos eléctricos y demás cosas, de entre todo eso había ahí un Super Mario Sunshine, lo agarre y la caja del juego estaba intacta, el disco sin ningún rayón, pregunté cuánto era y OMG 50$! submitted by Akenaton4815_ to VideojuegosMX [link] [comments]


2023.03.31 23:48 WildlyCanadian Looking for a new SUV/Hatchback, some questions.

Hey all,
I am located in Alberta, Canada and am looking to purchase a vehicle in the Edmonton area. Currently what's caught my eye is a 2019 Mitsubishi RVR, but it has 163,000 km on it which seems very high for a car that new. Is this a concern? Are there any known problems with this model to look out for? I move around a lot for work so I like the storage space an SUV provides, but I'm weary of getting something that won't last long (my current car turned out to be a shitter, that's why I'm in the market for something newer). I've never drove a manual but am willing to learn if it gets me a better vehicle for my money. The only issue with that is I'll be leaving the day after I get the vehicle for a rather long road trip.
I would be financing on a 60 month or lower term, would like to keep my biweekly payments to around 200 give or take. Anyone seeing anything I'm not?
Thank you all.
submitted by WildlyCanadian to whatcarshouldIbuy [link] [comments]


2023.03.31 23:47 NoEstablishment1559 G29 wheel. go to car/track. Severe understeer, Better traction out of corners, Slight improvement to the feel of losing front tires. Changed ride height, camber, toe, DF, wheel feedback setting, driving style. had to drive with slow in fast out mindset. Not preferred style but it’s faster

G29 wheel. go to catrack. Severe understeer, Better traction out of corners, Slight improvement to the feel of losing front tires. Changed ride height, camber, toe, DF, wheel feedback setting, driving style. had to drive with slow in fast out mindset. Not preferred style but it’s faster submitted by NoEstablishment1559 to granturismo [link] [comments]


2023.03.31 23:39 Line_Agile Rough

Rough submitted by Line_Agile to TopDrives [link] [comments]


2023.03.31 22:22 ADozenPigsFromAnnwn Sharing a ton of chabrette / musette repertoire freely available online

Hello piping folks, I don't know if anyone shared this on here in the past two years, since this sub is mainly SGHB-based, but I think that many of you may be interested. I hope this is a welcome suggestion for all the pipers here.
Éric Montbel, who's an absolute authority on the bagpipes of the Centre of France (essentially meaning the chabrette, but all of its repertoire is easily played on the musette - and on the border pipes as well), has reprinted in 2021 his book Carnet de notes - Cahier de répertoire pour la chabrette, which had been sold out for quite some time despite being an essential learning tool for that repertoire. Along with this, he made the recordings of all of the tunes contained in the book (around 200, sorted by type of tune and type of fingering - by the way, does anyone know what the English equivalent of entremain and plein-jeu is, if there is one?) freely available online at this link. [Edit: here you can also hear the recordings AND the original field recordings of old players and singers in the '70s and so on).
Also, if you don't know who he is, what the repertoire or this kind of bagpipes are like, this album is a great introduction to them.
Enjoy!
submitted by ADozenPigsFromAnnwn to bagpipes [link] [comments]


2023.03.31 20:42 Manual-Hub PEAVEY PA 200 (01) PDF MANUAL

PEAVEY PA 200 (01) PDF MANUAL submitted by Manual-Hub to u/Manual-Hub [link] [comments]


2023.03.31 19:40 SystemSpark [USA] [H]Bomberman 64 2, Boktai 2, .Hack Quaratine, Kid Dracula, Wild Guns, River City Girls, Scarface, Valkyrie Profile, Power Stone, Shantae, Switch/Wii/WiiU/PSP/PS1/PS2/PS3/PS4/PS5/DS/3DS/GBA/GB/NES/SNES/N64/NGC/Genesis/Saturn Games, amiibo, Controllers, Joy-Con,Nintendo Swag [W] Paypal F&F

Prices are subjective, negotiable, and do not include shipping.   Photos upon request
 
amiibo Price Condition
Zelda Loftwing 30 New In Box
Sanrio amiibo cards 12 Sealed Pack
Inkling Boy - Neon Green 39 Loose/Mint
Mario Cereal Box 15 Cereal Removed/Flattened
Isabelle Summer Outfit 40 Open Box
Cyrus/K.K./Reese 18 New In Box/Damaged box
Tom Nook 12 New In Box
Mabel 9 New In Box
 
Digital Codes Price Console
Mighty Switch Force 20 3DS
Shantae and the Pirate's Curse 20 WiiU
 
Switch Price Condition
Azure Striker Gunvolt Striker Pack 40 Sealed
Aggelos 40 Complete in Box
Bendy and the Ink Machine 30 Complete in Box
Cruel King and the Great Hero Storybook Edition 60 Complete in Box
Disgaea 1 Rosen Edition 100 Complete in Box
Ghostbusters The Video Game Remastered 30 Sealed
Metroid Dread Collector's Edition 110 Sealed, a few dings associated with shipping
Monster Hunter Stories 2 Collector's Edition 160 Sealed
River City Girls 200 Sealed, Best Buy Variant
Shantae Collector's Edition 150 Sealed
Shantae Risky's Revenge Collector's Edition 150 Sealed
Teenage Mutant Ninja Turtles Cowabunga Collection 30 Sealed
Unravel 2 30 Sealed
Yu-Gi-Oh Legacy of the Duelist: Link Evolution 18 Loose
Wonder Boy: The Dragon's Trap 40 Complete in Box
 
Wii Price Condition
Batallion Wars 2 11 Game and Case
Castle of Shikigami III 75 Complete in Box
Okami 10 Game and Case
 
WiiU Games Price Condition
Batman Arkham City Armored Edition 40 Sealed
Disney Infinity 2.0 15 Sealed
Mario Kart 8 15 Complete in Box
Nintendoland 10 Complete in Box
Star Fox Guard 10 Complete in Box
 
DS Price Condition
Super Scribblenauts 5 Loose
Witch's Wish 60 Loose
 
3DS Price Condition
Kid Icarus Uprising (Japanese) 40 Game, Manual, and Case (No Big Box)
 
GBA Price Condition
Boktai 2 200 Loose
Game & Watch Gallery 4 16 Loose, Torn Label
Lady Sia 30 Loose, EU import
Lady Sia 50 Loose. Label imperfections
Super Puzzle Fighter 2 60 Complete in Box
Super Mario Advance 13 No label
 
GB Price Condition
Alleyway 5 Loose
Kid Dracula 240 Loose
Pocket Monsters Red (Import) 10 Loose, still saves
 
NES Price Condition
Kid Icarus 180 Game, Box, and Manual; Box shows wear; Protective case for box and manual included
 
SNES Price Condition
Mortal Kombat II 15 Loose
Super Mario World 16 Loose
Super Scope 6 10 Loose
Wild Guns 270 Loose, Bad Label Damage
 
N64 Price Condition
Bomber Man 64 The Second Attack! 250 Loose
Pokemon Snap 15 Loose
 
Gamecube Price Condition
Final Fantasy Crystal Chronicles 14 Disc and case. Artwork is a little dinged up. No Manual
Harry Potter and the Chamber of Secrets 16 Complete in Box, blockbuster stickers on case.
Super Mario Sunshine 40 Game and Manual. Case included, but the artwork may be a reprint.
 
Sega Genesis Price Condition
Jurrassic Park 10 Loose cartridge, Sharpie on Label
Spider-Man 12 Loose cartridge, Label Damage
Genesis 6-Pak 18 Loose cartridge
 
Sega Saturn Price Condition
Vampire Savior (Import, Dark Stalkers 2) 40 Game and artwork, no spine slip. Some creases in the artwork.
 
Sega Dreamcast Price Condition
Power Stone 120 CIB
Power Stone 2 160 CIB
 
PSP Price Condition
Grand Theft Auto Liberty City Stories 19 Game and Case, Greatest Hits
Grand Theft Auto Liberty City Stories 14 Loose, Greatest Hits, Cracked Casing
Little Big Planet 9 Loose
Loco Roco 7 Complete in Box
Patapon 7 Loose
Silent Hill Origins 50 Complete In Box
Star Wars Battlefront Renegade Squadron 13 Complete in Box
 
PS1 Price Condition
Castlevania Chronicles 120 Loose
Chocobo's Dungeon 2 100 Complete in Box
Crash Bash 15 Complete in Box
Dark Stalkers 47 Loose
Dark Stalkers 3 47 Loose
Legacy of Kain: Soul Reaver 18 Loose
Silent Hill 105 Loose disc
Super Puzzle Fighter II Turbo 40 Complete in Box
Valkyrie Profile 325 Discs and Case, no manual
World of Dragon Warrior Torneko The Last Hope 80 Loose disc
 
PS2 Price Condition
Baldur's Gate Dark Alliance
Burnout 8 Complete in Box; Greatest Hits
Burnout 2 8 Loose Disc
Burnout 3 Takedown 11 Complete, Water Damage on back cover art
Burnout Dominator 9 Case and Disc, Disc has superficial scratches but still boots
Burnout Revenge 10 Complete, Greatest Hits
Castlevania Curse of Darkness 60 Loose, Disc has light scratching
Crash Bandicoot The Wrath of Cortex 10 Greatest Hits, Used, Disc and Case
Dragon Ball Z Budokai 11 Complete in Box
Dragon Ball Z Budokai Tenkaichi 15 Complete in Box; Greatest Hits
Final Fantasy X 6 Greatest Hits, Used, Disc and Case
Final Fantasy X-2 6 Complete; Greatest Hits
God of War II 13 Complete; Greatest Hits
Grand Theft Auto Vice City 10 Disc, Case, Poster, No Manual
.Hack Quaratine 300 Game, Anime Disc, and Case. Missing Manual
Jak and Daxter 10 Greatest Hits, Used, Disc and Case
Marvel vs Capcom 2 60 Cracked Disc, won't boot for me. Comes with case, no manual
Metal Gear Solid 2 Sons of Liberty 10 Greatest Hits, Used, Disc and Case
Naruto Ultimate Ninja 2 10 Disc and Case
Need for Speed Underground 10 Greatest Hits, Used, Disc and Case
Need for Speed Underground 2 17 Greatest Hits, Used, Disc and Case
Need for Speed Hot Pursuit 2 10 Greatest Hits, Used, Disc and Case
Resident Evil Dead Aim 50 Game and Case, No manual
Scarface 40 Complete; Greatest Hits
Star Wars Battlefront II 10 Disc and Case
Tekken Tag Tournament 10 Disc and Case; Greatest Hits
 
PS3 Price Condition
Castlevania Lord of Shadow Collection 30 Loose
 
PS4 Price Condition
APEX Construct 15 Sealed
 
PS5 Price Condition
Battlefield 2042 20 Complete in Box
 
XBOX One Price Condition
Watchdogs 15 Sealed
 
Consoles Price Condition
Monster Hunter Rise Edition Switch 420 New in Box (No game code)
White OLED Nintendo Switch 400 New in Box
OLED Switch Tablet 250 New/Unused Tablet Only
Legend of Zelda Game & Watch (35th Anniversary) 50 New in Box
SNES Jr. 120 Includes Deck, RF Coax Cable, Third Party AC Adapter, and Third Party Controller. Small crack on the corner.
 
Controllers Price Condition
Fortnite Joy-Con Set 120 Comes from the Fortnite Edition Console, never used
Joy-Con Grip 8 Bagged/Unused - Came with console
Oculus Quest 1/Rift S Left Controller 115 Used but very good condition. Comes with silicon case
Oculus Quest 1/Rift S Right Controller 115 Used but very good condition. Comes with silicon case
Platinum Gamecube Controller 20 Third Party, no nintendo logo, wired, good condition
Joy-Con (Left/Neon Blue) 35 Good, no drift
Joy-Con (Left/Gray) 35 Good, no drift
Joy-Con (Right/Neon Blue) 35 Good, no drift
Joy-Con (Right/Neon Red) 35 Good, no drift, Factory refurbished
SNES Controller 10 Third Party, no nintendo logo
SPIN Z WiiU Pro Controller 25 Black, Near Mint
SPIN Z WiiU Pro Controller 25 Black, Near Mint
Gray Wavebird w/Receiver 90 All OEM, the receiver and controller have a discremepncy on channels, but everything works as intended.
WiiU Pro Controller 35 Black, OEM, Good condition
 
Misc. Price Condition
Switch Dock (Black) 40 Good
Black MagicGate 8MB PS2 Memory Card 20 Has Free McBoot loaded onto the card
Blue MagicGate 8MB PS2 Memory Card 20 Has Free McBoot loaded onto the card
Yellow Nyko MagicGate 8MB PS2 Memory Card 20 Has Free McBoot loaded onto the card
Super Smash Bros Ultimate Nintendo Switch ConsoleBox Only 90 Empty Box, good condition
Animal Crossing Nintendo Switch Console Box Only 20 Empty Box, good condition
Pokemon Dialga & Palkia Switch Lite Box Only 30 Empty Box, good condition
Fortnite Nintendo Switch Console Box Only 20 Empty Box, good condition
The Art of Splatoon 2 300 Sealed
Kid Icarus Uprising Players Guide (Imported, no AR cards) 30 Shows a little wear
Nintendo Switch AC Adapter 20 Unused in original bag, Authentic Nintendo Adapter
Super Smash Bros. Ultimate Pre-Order Coin 15 Sealed
Breath of the Wild Sheikah Coin 25 From BotW Special Edition, Good condition
Pokken Art Cel Pre-Order Bonus 7 Sealed
Blastoise New 3DS Plates 150 Plates are mint and unused
Nintendo 3DS Stand 30 OEM, Came with Kid Icarus Uprising
Kid Icarus AR Card Set (205/404) 600 Contains 205 different US cards, no duplicates. This is roughly half the entire set. An itemized list can be provided upon request.
Shantae Risky's Revenge 2 LP Soundtrack Vinyl 55 Sealed
 
Cases Price Condition
Dot Hack (.HACK) Infection 20 Case & Manual
Dot Hack (.HACK) Mutation 20 Case only
Dot Hack (.HACK) Outbreak 30 Case & Manual
God of War Chains of Olympus 15 Case and Manual Only
 
Freebies Price Condition
Gold Game & Watch Stand Free with purchase Gold Game & Watch stand meant for the 35th Anniversary Edition Zelda G&W, but likely works with others.
Playstation 2 IDE Connector Free with purchase Upgraded my HD Adapter to SATA, these are the old/leftover connectors.
Leapster Games Free with purchase
 
submitted by SystemSpark to GameSale [link] [comments]


2023.03.31 18:59 sage0021 [US] [H] Consoles N64 Snes Nes WiiU Genesis. Games Switch-Nes Sega Playstation. Misc items Zelda Final Fantasy [W] Paypal


Shipping is not included in prices. Reasonable offers will be considered. **I am only accepting Paypal FF at this time.**

Consoles:


Switch Games: All Switch games are 1 owner purchased new.



SNES games:


Genesis games:


NES games:


DS/3DS games:


Wii Games:


Wii U Games:


N64 Games:

Playstation ps1 games:



Playstation 2 ps2 games:


PSP Games:
https://imgur.com/a/Cr2IojG


Misc items:

submitted by sage0021 to GameSale [link] [comments]


2023.03.31 18:46 Arbeitsunrecht Wie soll das mit diesem Union Busting funktionieren?

Ein gutes Beispiel dafür wie #Lieferando Betriebsratsmitglieder systematisch stresst, die dieses Ehrenamt übernommen haben, um sich für ihre rund 1.200 Kolleginnen und Kollegen in Berlin einzusetzen:
Raum für Betriebsversammlung trotz Vertrags und Vereinbarung über Vorkasse nicht gezahlt. Es werden mehrere hundert Beschäftigte erwartet. (Pressemitteilung des Berliner Lieferando-Betriebsrats)
#UnionBusting Volle Solidarität! Für Demokratie in Wirtschaft & Betrieb!
submitted by Arbeitsunrecht to arbeitsunrecht [link] [comments]


2023.03.31 17:21 DUCK_04 Why did the price of these cards drop so much?

Why did the price of these cards drop so much?
The UCL card went up by 10 million while the other cards are dropping in price. Are the UCL cards better?
submitted by DUCK_04 to FUTMobile [link] [comments]