First united methodist church martinsville va

La Crescent, MN

2015.01.04 08:31 vanjan14 La Crescent, MN

A place for people who live or have lived in or near La Crescent, MN to discuss news, issues, and community events!

2017.05.29 10:27 LazyLooser Coquina, tiny shells, is a natural seashell rock found in St. Augustine.

Coquina, tiny shells, is a natural seashell rock found in St. Augustine. The Castillo is the most significant building using this stone, but in St. Augustine 1st, the one remaining British building and 2nd period Spanish buildings are made of coquina. The Island itself was originally called La isla de la cantera (Quarry island) before it was named Anastasia Island. The rock was cut by hand and moved to Quarry creek and floated across the bay to the Castillo and city.

2023.03.28 19:45 DohB01 Krystexxa's Patient Profile Guide: Key Characteristics and Prerscribing Info

Krystexxa's Patient Profile Guide: Key Characteristics and Prerscribing Info

KRYSTEXXA® (pegloticase) with methotrexate

Improved efficacy Reduced infusion reactions Improved confidence
KRYSTEXXA with methotrexate can change the course of uncontrolled gout
Artist’s rendition. Hand images are DECT images of one patient taken in the MIRROR RCT. Best results seen at 6 to 12 months. Optimal treatment duration has not been established.
Individual results may vary.DECT, dual-energy computed tomography; MIRROR, Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase; RCT, randomized controlled trial.

Improved efficacy

>80% relative improvement in patient response; 71% vs 39% complete response* compared to KRYSTEXXA alone at Month 61

Reduced infusion reactions

87% relative reduction in infusion reactions; 4% vs 31% compared to KRYSTEXXA alone1

Improved confidence

With fewer infusion reactions and improved patient response, you can confidently reduce years of urate burden1


KRYSTEXXA with methotrexate may be right for your patients with uncontrolled gout

Learn about Bet, your new patient

Have a patient who might be ready for KRYSTEXXA?

Connect with the KRYSTEXXA team to discuss the ACR Guidelines and treatment criteria.
Request Support

Horizon By Your Side: a Patient Support Program
The dedicated members of the Horizon By Your Side team take a personalized approach to meet your patients' unique treatment needs as well as those of their caregiver(s). Once a patient is enrolled in the program, the team will partner with them to discuss support options and the best path forward.
Sign Up Now

Initiate your patient’s enrollment in Horizon By Your Side by submitting the Patient Enrollment Form (PEF). Your patient must complete enrollment to access our patient-focused services and resources.

DocuSign® eSignature Patient Enrollment Form. Begin the form and send to your patient via email to complete via DocuSign®. Begin Here
Downloadable Patient Enrollment Form. Print, complete with your patient, and fax the form to 877-633-9522 OR email it to [[email protected]](mailto:[email protected]).
Download Form
Download Patient Enrollment Form Guide
Download Form - Spanish

Support designed with your patient in mind

Whether your patient needs personalized support, insurance and financial assistance, or helpful resources, the Horizon By Your Side team is here to help them throughout their treatment journey.

Once you’ve prescribed KRYSTEXXA, the Horizon By Your Side team is here to assist your patient every step of the way
*The Horizon Commercial Co-Pay Program may be available to patients who meet the following minimum criteria:
  • Patient’s prescription cannot be paid in part or in full by any government-funded program including but not limited to: Medicare, Medicare Part D, Medicaid, Medigap, VA, CHAMPUS, Department of Defense (DOD), TRICARE, or any state, patient foundation, or other pharmaceutical program
  • Patient is prescribed a covered Horizon rare disease medication for an indication approved by the Food and Drug Administration; the indication for each product is shown in its prescribing information
  • Patient is a resident of the United States
  • Patient must be commercially insured and have financial responsibility for a portion of the drug and/or infusion cost if applicable
The assistance offered under this co-pay program is subject to additional terms and conditions, including but not limited to the following:
Terms and Conditions: Offer cannot be combined with any other rebate or coupon, free trial, or similar offer for the specified prescription. Not valid for prescriptions reimbursed in whole or in part by any government-funded program including but not limited to Medicare, Medicare Part D, Medicaid, Medigap, VA, CHAMPUS, DOD, TRICARE, or any state, patient foundation, or other pharmaceutical program. Offer good only in the United States at participating specialty pharmacies or sites of care. Offer not valid where otherwise prohibited by law, for example by applicable state law prohibiting co-pay cards. Horizon reserves the right to rescind, revoke, or amend offer without notice. The selling, purchasing, trading, or counterfeiting of any co-pay card or benefits is prohibited by law. This co-pay program is not insurance and is not intended to substitute for insurance. Age for eligibility is dependent on product indication.
Participating Pharmacies or Healthcare Providers: By using this co-pay program, you acknowledge and confirm that the prescription will not be reimbursed in whole or in part by any government-funded program (such as, without limitation, Medicare, Medicaid, VA, DOD, TRICARE) and the patient and prescription meet the eligibility criteria set forth in the terms and conditions. You are responsible for reporting the receipt of the co-pay program benefits as required by an insurer, payor, or applicable law or regulation.
Patients: By enrolling in this co-pay program, you acknowledge and confirm that you and the prescription meet the eligibility requirements set forth in the terms and conditions, including that the prescription will not be reimbursed in whole or in part by any government-funded program (such as, without limitation, Medicare, Medicaid, VA, DOD, TRICARE). You may not seek any claims to government payors or other payors or insurers for this prescription. You may not seek reimbursement from any health savings, flexible savings, or other healthcare reimbursement account for any amounts received from the co-pay program. You are responsible for reporting the receipt of the co-pay program benefits as required by an insurer, payor, or applicable law or regulation.



  • Anaphylaxis and infusion reactions have been reported to occur during and after administration of KRYSTEXXA.
  • Anaphylaxis may occur with any infusion, including a first infusion, and generally manifests within 2 hours of the infusion. Delayed hypersensitivity reactions have also been reported.
  • KRYSTEXXA should be administered in healthcare settings and by healthcare providers prepared to manage anaphylaxis and infusion reactions.
  • Premedicate with antihistamines and corticosteroids and closely monitor for anaphylaxis for an appropriate period after administration of KRYSTEXXA.
  • Monitor serum uric acid levels prior to each infusion and discontinue treatment if levels increase to above 6 mg/dL, particularly when 2 consecutive levels above 6 mg/dL are observed.
  • Screen patients at risk for glucose-6-phosphate dehydrogenase (G6PD) deficiency prior to starting KRYSTEXXA. Hemolysis and methemoglobinemia have been reported with KRYSTEXXA in patients with G6PD deficiency. KRYSTEXXA is contraindicated in patients with G6PD deficiency.


  • In patients with G6PD deficiency.
  • In patients with history of serious hypersensitivity reactions, including anaphylaxis, to KRYSTEXXA or any of its components.


Gout Flares: An increase in gout flares is frequently observed upon initiation of anti-hyperuricemic therapy, including KRYSTEXXA. Gout flare prophylaxis with a non-steroidal anti-inflammatory drug (NSAID) or colchicine is recommended starting at least 1 week before initiation of KRYSTEXXA therapy and lasting at least 6 months, unless medically contraindicated or not tolerated.
Congestive Heart Failure: KRYSTEXXA has not been formally studied in patients with congestive heart failure, but some patients in the pre-marketing placebo-controlled clinical trials experienced exacerbation. Exercise caution in patients who have congestive heart failure and monitor patients closely following infusion.


The most commonly reported adverse reactions (≥5%) are:
KRYSTEXXA co-administration with methotrexate trial:
KRYSTEXXA with methotrexate: gout flares, arthralgia, COVID-19, nausea, and fatigue; KRYSTEXXA alone: gout flares, arthralgia, COVID-19, nausea, fatigue, infusion reaction, pain in extremity, hypertension, and vomiting.
KRYSTEXXA pre-marketing placebo-controlled trials:
gout flares, infusion reactions, nausea, contusion or ecchymosis, nasopharyngitis, constipation, chest pain, anaphylaxis, and vomiting.


KRYSTEXXA® (pegloticase) is indicated for the treatment of chronic gout in adult patients who have failed to normalize serum uric acid and whose signs and symptoms are inadequately controlled with xanthine oxidase inhibitors at the maximum medically appropriate dose or for whom these drugs are contraindicated.
Limitations of Use: KRYSTEXXA is not recommended for the treatment of asymptomatic hyperuricemia.
Please see Full Prescribing Information, including Boxed Warning.
submitted by DohB01 to u/DohB01 [link] [comments]

2023.03.28 18:47 frozen_lemons A long, but important open letter regarding the Nashville school church shooting

Hello everyone, it pains me to write this open letter about the shooting, but I feel it is extremely important to do so
I was raised Christian, left, and then came back to the faith. However, a few years ago I left the faith, and am now pagan. The reason for my departure was not because I am queer, rather, it was over a theological issue surrounding the legitimacy of Jesus's claim to be the messiah.
However specifics are not important. What is important is that we recognize the conflict between Christianity and the LGBTQ community is not as black and white as it appears to many people. What I mean by that is, a person can be both LGBTQ and Christian. It is not one or the other.
To start with, I am not going to "both sides" this thing, as the power dynamics are extreme. On one hand is the worlds largest religion, with billions of followers across the globe. The faith has changed the course of history, and has been the dominant force over politics for nearly two thousands years. To this day, the faith influences laws even in supposed secular countries.
There is no equivalent of this for the LGBTQ community.
During the Age of Enlightenment, the long held traditional teaching of the church started to be called into question. This, of course, was, and is, not inherently bad. The faith was forced upon people, and used to justify murder, racism, sexism, homophobia, transphobia, and even genocide. There was a period of time in which those who questioned the teachings of the church at best were exiled and at worst killed.
The Bible was used as justification for slavery, yet many African Americans found comfort in the teachings of Christ. Why? Because the Bible can be interpreted in an infinite number of ways. This is the same with any religion. Think of how the Kahanists have weaponized the Torah to justify human rights abuse of the Palestinians, or how the ISIS has used the Quan to justify genocide. Even Atheism has been weaponized for racism and xenophobia.
However, while the Bible is open to interpretation, when going back to the original text, and putting things into context, it is clear that often the basic facts have been twisted to fit a persons pre-existing belief. Take for example, the Bible stance on homosexuality. Here is a pretty good break down of how the words have been twisted to fit the views of homophobes. I would also encourage you to go back and listen to BTB two episodes on How The Rich Ate Christianity, and read the book "One Nation Under God: How Corporate America Invented Christian America" by Kevin Kruse, a historian at Princeton University.
Of course, none of this means ex-Christians, or even current Christians, should be expected to forgive the church, especially to those who it has hurt. I know first hand how the faith can be destructive. I have been told I was going to be damned to hell. I was told that my place is not in college but in a kitchen. I have been told that women missionaries are heretical. I have had nightmares of burning in a lake of fire. I know damn well what happens when Christianity is weaponized.
At the same time, this does not justify violence. I think about the Church burnings in response to the abuse of Native American children at boarding schools. Yet 700,000 Native Americans are estimated to be Catholic. Millions of LGBTQ people identify as Christian. Churches such as The United Methodist Church have literally split over the conflict of same-sex marriage, with one side approving and the other side wishing to stick to "traditional" values. As of writing this (March 28, 2023 12:48 PM Eastern Time) the investigation is still ongoing. We will learn more over the course of the following weeks and months, but it does appear that this was a hate crime.
And yes, I use the words "hate crime" because if it turns out to be that she attacked the church based on religion alone, that is a hate crime according to Tennessee state law: "A crime committed by a perpetrator who intentionally selected the person or the property that was damaged or otherwise affected by the crime, in whole or in part, because of the perpetrator’s belief or perception regarding the race, religion, color, disability, sexual orientation, national origin, ancestry, or gender of that person or the owner or occupant of that property."
I should also note that I am well aware of bad faith actors who will weaponize this tragedy to target the LGBTQ community, especially trans people. The transphobia and hate on Twitter is already terrible, but after the shooting, it has become especially vile. I know, it is frustrating, because there is nothing we can do about it. Conservatives will take this and run with it, use it as propaganda to further flame bigotry against trans people. Conservatives have long screamed that the US should kick out Muslims and Latin American immigrants. They have bombed abortion clinics, they have shot up gay night clubs (and even an LGBTQ friendly church in 2008.) Yet there has been no mainstream support in society of any kind to restrict the rights of conservative Christians or ban anti-abortion extremist groups. It's unfortunate, but this is the world we live in.
And no, as I mentioned before, there is no "both sides." The burning of churches (and even this shooting, if it turns out to be a hate crime) is nothing compared to what the faith has done.
All I'm saying is that this is not a black and white issue like so many people believe.

When you attack the Church as whole, you are attacking millions of people who you claim to be defending.

This letter has gotten to be a lot longer than I originally intended, but I feel that it needed to be said. Feel free to add your opinions. But just know that any bigotry or hate will be removed.
Thanks for coming to my Ted Talk,
submitted by frozen_lemons to behindthebastards [link] [comments]

2023.03.28 18:13 AnkalaevWillBeTop5 What can be done to stop the decline of mainline Protestantism?

I want to ask actual mainline Protestants this so that the thread hopefully doesn’t turn into a conservative vs. liberal bashing session.
It is very clear now that more theologically liberal (meaning things like: don’t believe the Bible is infallible, LGBT affirming, pro-abortion, allow female church leaders, etc.) denominations are experiencing major decline. Some of the main examples would be The Episcopal Church, PCUSA, United Methodists, ELCA, Disciples of Christ, etc.
So, from the perspective of liberal Christians within these churches, what should be done? Do you guys think the declines could be stopped? Do you expect your church to be around in the future? What should be done to grow or retain members better?
submitted by AnkalaevWillBeTop5 to Christianity [link] [comments]

2023.03.28 17:16 grunt2-9 Who signs the ChampVA application?

Who signs the ChampVA application? submitted by grunt2-9 to VeteransBenefits [link] [comments]